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DNA Analysis Laboratory

The Core DNA Analysis Lab uses capillary electrophoresis for DNA sequencing and fragment analysis. Sequencing uses fluorescent dyes to label partial copies of DNA provided by NIU scientists. Typically the nucleotide sequence of plasmids or PCR products are determined. The same equipment is used for fragment analysis, but the PCR products themselves are labeled. An internal size standard allows for precise size determination of these products. This information is commonly used for genotyping studies to distinguish between closely related individuals or populations.

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