DNA Sequencing Request

DNA Core Facility
Plant Molecular Biology Center
303 Montgomery
Northern Illinois University
DeKalb Illinois 60115

Telephone: 815 753 0638                            Cost is $10 per sample for NIU scientists
Fax: 815 753 7855
 
email: sgrayburn@niu.edu
 
 

Name_____________________________________________________ Phone_______________

Email address_______________________________________________ Date _______________

Account to be billed:_________________________________________
 
 
 
 

            Sample            ss/ds/pcr?      Size in kb       Primer Name    Comments
                                                       insert/vector

1 _______________ _________ ____________ ___________ __________________________

2 _______________ _________ ____________ ___________ __________________________

3 _______________ _________ ____________ ___________ __________________________

4 _______________ _________ ____________ ___________ __________________________

5 _______________ _________ ____________ ___________ __________________________

Primers available at the core facility:

T7: 5' TAA TAC GAC TCA CTA TAG GG 3'

SP6: 5' ATT TAG GTG ACA CTA TAG 3'

T3: 5' AAT TAA CCC TCA CTA AAG GG 3'

MF: (M13 -21 forward primer): 5' TGT AAA ACG ACG GCC AGT 3'

MR1: (M13 reverse primer): 5' AAC AGC TAT GAC CAT G 3'

MR2: (M13 reverse primer): 5' TTT CAC ACA GGA AAC AGC 3'

polyT: 5' TTT TTT TTT TTT TTT (ACG)NN

Notes:

-It is the requestor's responsibility to obtain approval for use of recombinant DNA from the appropriate institutional biosafety committee
-DNA should be clean and of uniform size before sequencing.
-Template that is adequate for manual sequencing may not be pure enough for automated sequencing.
-If template DNA is purified using an untested protocol, supply a single sample to determine if modifications are needed.
-Supply double-stranded (ds) plasmid DNA at 250 ng/ uL in water
-Supply PCR products at 30 ng / uL in water. Primers and free dNTPS must be removed prior to sequencing.
-Supply single-stranded (ss) DNA at 50 ng / uL in water.
-Label each tube on the top.
-Custom sequencing primers should be at least 18 bases long, have melting temperatures above 45 C, and lack potential secondary structure. Provide custom primers at 10 ng/ uL in water and include the sequence or quantity of each base under `Comments'. Assume 1 ODU (A260)=33 ug of ss oligonucleotide in 1 mL water.