Professor
Educational Background
Ph.D., Apto Cum Laude, CIB-CSIC/University of Alcala de Henares, Madrid, Spain (Microbiology), 1995
M.S., University of Alcala de Henares, Madrid, Spain(Microbiology and Parasitology) 1989
B.S., University of Alcala de Henares, Madrid, Spain (Biological Science) 1987
Contact: Ana M. Calvo
amcalvo@niu.edu
Office: MO 341, (815) 753-0451
Lab: (815) 753-1468
Depart. of Biological Sciences
Northern Illinois University
Additional Experience
- Postdoctoral stay (Molecular Microbiology September-December 2001). Michigan State University, East Lansing, MI
- Postdoctoral stay (Molecular Microbiology-Functional Genomics July-August 2001) Texas A&M University, College Station, TX
- Postdoctoral Stay (Molecular Microbiology 1996-June 2001). Texas A&M University, College Station, TX
Graduate Research Assistantship Opening in Fungal Genetics and Molecular Biology
Representative Publications
Laskowski-Peak MC, Calvo AM, Rohrssen J., and Smulian AG. 2012. VEA1 is Required for Cleistothecial Formation and Virulence in H. capsulatum. Fungal Genetics and Biology. In press.
Myung, K., N. C. Zitomer, M. Duvall, A. E. Glenn, R. T. Riley and A. M. Calvo. 2012. The conserved global regulator VeA is necessary for symptom production and mycotoxin synthesis in maize seedlings by Fusarium verticillioides. Plant Pathology. 61:152-160.
Padamsee M, Kumar TK, Riley R, Binder M, Boyd A, Calvo AM, Furukawa K, Hesse C, Hohmann S, James TY, LaButti K, Lapidus A, Lindquist E, Lucas S, Miller K, Shantappa S, Grigoriev IV, Hibbett DS, McLaughlin DJ, Spatafora JW, Aime MC. 2012. The genome of the xerotolerant mold Wallemia sebi reveals adaptations to osmotic stress and suggests cryptic sexual reproduction. Fungal Genet Biol. 49:217-26.
Chettri P, Calvo AM, Cary JW, Dhingra S, Guo Y, McDougal RL, Bradshaw RE. 2012. The veA gene of the pine needle pathogen Dothistroma septosporum regulates sporulation and secondary metabolism. 49:141-51.
Calvo AM and Dhingra S. 2011. Conserved regulatory mechanisms controlling aflatoxin and sterigmatocystin biosynthesis. In: Aflatoxin-Biochenistry and Molecular Biology. Ed.: Ramon G. Guevara-Gonzalez. pg 67-89. ISBN 978-953-307-395-8.
Baidya S, Cary JW, Grayburn WS, Calvo AM. Role of nitric oxide and flavohemoglobin homolog genes in Aspergillus nidulans sexual development and mycotoxin production. Appl. Environ. Microbiol. 2011 77:5524-8.
Atoui A, Kastner C, Larey CM, Thokala R, Etxebeste O, Espeso EA, Fischer R, Calvo AM 2010. Cross-talk between light and glucose regulation controls toxin production and morphogenesis in Aspergillus nidulans. Fungal Genet Biol. 2010 Sep 17. [Epub ahead of print
Duran R.M., Cary J.W, Calvo A.M. 2010.Role of the Osmotic Stress Regulatory Pathway in Morphogenesis and Secondary Metabolism in Filamentous Fungi. Toxins, 2: 367-381
Chanda A., Roze, L., Kang S., Hicks G., Railhel., N., Calvo A., Linz J. A key role for vesicles in fungal secondary metabolism. Proceedings of the National Academy of Sciences of the United States of America. Proc Natl Acad Sci U.S.A. 2009 Nov 17; 106:19533-8.
Duran RM, Cary JW and Calvo AM. The role of veA on Aspergillus flavus infection of peanuts, corn and cotton. 2009. Open Mycology journal (open access) 3, 27-36. .pdf
Myung K, Li S, Butchko RAE,Busman M, Proctor RH, Abbas HK, Calvo AM. FvVE1 regulates biosynthesis of the mycotoxins fumonisins and fusarins in Fusarium verticillioides. J. Agric. Food Chem. 2009. [epub ahead of print]
Araújo-Bazán L, Dhingra S, Chu J, Fernández-Martínez J, Calvo AM, Espeso EA Importin alpha is an essential nuclear import carrier adaptor required for proper sexual and asexual development and secondary metabolism in Aspergillus nidulans. Fungal Genet Biol. 2009 Mar 24. [Epub ahead of print]
Cary J, Szernzen L, and Calvo AM. Regulation of Aspergillus flavus aflatoxin biosynthesis and development. In Mycotoxin Prevention and control in Agriculture. Eds.: David Kendra and Michael Appell. 2009. pg. 183-203.
Cary J and Calvo AM. Regulation of aflatoxin biosynthesis. Journal of Toxicology: Toxin Reviews. 2008. 27: 347-370
Li S., Calvo AM, Yuen GY, Du L Harris SD. 2008. Induction of Cell Wall Thickening by the Antifungal Compound Dihydromaltophilin Disrupts Fungal Growth and Is Mediated by Sphingolipid Biosynthesis. Journal of Eukaryotic Microbiology, 56: 182-187.
Calvo A.M. 2008. The VeA regulatory system and its role in morphological and chemical development in fungi. Fungal Genetics and Biology 45:1053-61.
Atoui A, Bao D, Kaur N., Grayburn WS, Calvo AM. 2008. The MAP-kinase mpkB is necessary for normal secondary metabolism in Aspergillus nidulans. Appl. Environ. Microbiol. 74:3596-600.
Purschwitz J, Müller S, Kastner C, Schöser M, Haas H, Espeso EA, Atoui A, Calvo AM, Fischer R. Functional and Physical Interaction of Blue- and Red-Light Sensors in Aspergillus nidulans. Current Biolology 2008. 18:255-9.
Roze LV, Beaudry RM, Arthur AE, Calvo AM, Linz JE. Aspergillus volatiles regulate aflatoxin synthesis and asexual sporulation in Aspergillus parasiticus. Appl Environ Microbiol. 2007. 73:7268-76.
Paoletti M, Seymour FA, Alcocer MJ, Kaur N, Calvo AM, Archer DB, Dyer PS. Mating Type and the Genetic Basis of Self-Fertility in the Model Fungus Aspergillus nidulans. Curr Biol. 2007 Jul 30 [Epub ahead of print] pdf
Cary JW, Obrian GR, Nielsen DM, Nierman W, Harris-Coward P, Yu J, Bhatnagar D, Cleveland TE, Payne GA, Calvo AM. Elucidation of veA-dependent genes associated with aflatoxin and sclerotial production in Aspergillus flavus by functional genomics. Appl Microbiol Biotechnol. 2007 Jul 24 [Epub ahead of print] pdf
Li S, Bao D, Yuen G, Harris SD, Calvo AM. basA regulates cell wall organization and asexual/sexual sporulation ratio in Aspergillus nidulans. Genetics. 2007. 176:243-53 pdf
Stinnet S., Espeso E., Cobeno L., Arujo-Bazan L. and Calvo A.M. 2007. VeA subcellular localization is dependent on the improtin alpha carrier and on light in the filamentous fungus Aspergillus nidulans. Molecular Microbiology. 63:242-55. Epub 2006 Dec 5.
Cary JW, Ehrlich K, Kale SP, Calvo A.M., Bhatnagar D, Cleveland TE. 2006 Regulatory Elements in Aflatoxin Biosynthesis. Mycotoxin Research 22:105-109
Li S., Myung K., Guse D., Donkin B., Proctor RH, Grayburn W.S. and Calvo A.M. 2006. FvVE1 regulates filamentous growth, the ratio of microconidia to macroconidia and cell wall formation in Fusarium verticillioides. Molecular Microbiology. 62:1418-32. Epub 2006 Oct 18.
Duran R.M., Cary J. W. and Calvo A.M. 2007. Production of Cyclopiazonic acid, Aflatrem and Aflatoxin by Aspergillus flavus is regulated by veA, a gene necessary for sclerotial formation. Applied Microbiology and Biotechnology. 73:1158-68. Epub 2006 Sep 19.
Calvo A.M., Bok J.W., Brooks W. and Keller N.P. veA is required for toxin and sclerotial production in Aspergillus parasiticus. Apply Environmental Microbiology 2004. 70:4733-9. pdf
Wilson R.A., Calvo A.M., Chang P-K and Keller N.P. Characterization of the Aspergillus parasiticus delta12-desaturase gene: a role for lipid metabolism in the Aspergillus/plant interaction. Microbiology. 2004.150:2881-8. pdf
Calvo A.M. 2004. Mycotoxins. In: Toxins in Food. Dabrowsky W. and Sikorski Z. (Eds.) CRC Press. Boca Raton, Florida, pg 215-237
Roze L.V., Calvo A.M., Gunterus A., Beaudry R., Kall M., and Linz J.E.. Ethylene modulates development and toxin biosynthesis in Aspergillus likely via an ethylene sensor-mediated signaling pathway. Journal of Food Protection. 2004. 67: 438-447.
Research Specialization:
Molecular Studies of Agriculturally and Medically Important Fungi
Dr. Calvo with Lab Group - click to view larger
Publications continued…
Kato N., Brooks W. and Calvo A.M. The expression of sterigmatocystin and penicillin genes in Aspergillus nidulans. Eukaryotic Cell.2003; 2: 1178-1186. pdf
Calvo A.M., Wilson R.A., Bok J. and Keller N.P. Relationship between natural product metabolism and fungal development. Microbiology and Molecular Biology Reviews, 2002. 66:447-59. pdf
Calvo A.M., Gardner H.W. and Keller N.P. Genetic connection between fatty acid metabolism and sporulation in Aspergillus nidulans. Journal of Biological Chemistry, 2001, 276:25766-74 pdf
Calvo A.M, Hinze L.L., Gardner H.W. and Keller N.P. Sporogenic effect of polyunsaturated fatty acids on development of Aspergillus spp. Applied and Environmental Microbiology, 1999, 65:3668-3673 pdf
Calvo A.M., Desjardins A., Keller N.P. and Trail, F. Effects of the plant lipid metabolite CP2 on morphological development and biosynthesis of natural products in Aspergillus spp. In preparation.
Calvo A.M., Copa-Patiño J.L., Alonso A. and González A.E. 1998. Studies of the production and characterization of laccase activity in the basidiomycete Coriolopsis gallica, an efficient decolorizer of alkaline effluents. Archives of Microbiology, 171:31-36
Calvo A.M., Terrón M.C., Fidalgo M.L., Pelayo J.M., Galletti G.C. and González A.E. 1995. Py-GC-MS Characterization of wheat straw alkaline-cooking effluents after biological treatment with the fungi Phanerochaete chrysosporium and Ganoderma australe. Analytical Chimica Acta, 309:145-152
Calvo A.M., Galletti G.C. and González A.E. 1995. Paper wastewater analyses by Py/GC/MS during biological treatment with the fungi Coriolopsis gallica and Paecilomyces variotii. Journal of Analytical and Applied Pyrolisis, 33:39-50
Pal M., Calvo A.M., Terrón M.C. and González A.E. 1995. Changes produced in the integral sugarcane bagasse after SSF by the edible mushroom Flammulina velutipes and the white-rot fungus Trametes versicolor. World Journal of Microbiology and Biotechnology, 11:541-545
Terron M.C., Calvo A.M., Fidalgo M.L., Manzanares P., Ballesteros M., Martinez A.T., Martin C. and Gonzalez A.E. Chemical characterization and biological decolorization of straw soda pulping effluents. Eds. M. Kuwahara and M. Shimada. Biotechnology in Pulp and Paper Industry, Uni Publishers Co., Ltd., Kyoto, Japan. 1992. pp 51-56.
Calvo A.M., Martinez A.T. and Gonzalez A.E. Biological decolorization of effluent from paper industry by fungi. Med. Fac. Landbouww. 1991. 56: 1565-1567.
Jimenez A., Rodriguez F., Calvo A.M. and Casado N. 1989. A comparative study of malate dehydrogenase in the genus Trichinella. Trichinellosis-ITC 7, Ed. C. Tanner, CSIC Press, Madrid, Spain. pp 53-58.