Northern Illinois University

Department of Biological Sciences

Professor W. Elwood Briles - Faculty - Cell Biology

photo of Professor and Mrs. Briles

Mrs. Ruth Briles (left) and Dr. Elwood Briles (right)

Educational Background

Ph.D., 1948, University of Wisconsin

B.A., 1941, University of Texas 

Fields of Interest: Immunology; immunogenetics; molecular genetics 

Contact: W. Elwood Briles 
Dept. Biological Sciences
Northern Illinois University 
DeKalb, IL 60115-2861
Office: 815-753-7840, MO415

Course / Lab Information

Representative Publications

To see entire CV click here

?Shiina, T., Briles, W.E., Goto, R.M., Hosomichi, K., Yanagiya, K., Shimizu, S., Inoko, H., and Miller, M.M. 2007. Extended Gene Map Reveals Tripartite Motif, C-Type Lectin, and Ig Superfamily Type Genes within a Subregion of the Chicken MHC-B Affecting Infectious Disease. Journal of Immunology 178:7162-7172.

Collisson, E.W., S.H. Seo, J. Dzielawa, W.E. Briles, and J. Pei. 2001. Syngeneic DC8+, T, lymphocytes protect chicks from acute infectious bronchitis viral infections and respiratory illness. In: K.A. Schat (ed.), Current Progress on Avian Immunology Research, pp. 220-225. American Association of Avian Pathologists, Kennett Square, Pennsylvania.

Briles, W.E. 2001. Design of parent stocks facilitating simultaneous testing of ultiple alloantigen systems for immune response. In: K.A. Schat (ed.) Current Progress on Avian Immunology Research, pp. 177-181. American Association of Avian Pathologists, Kennett Square, Pennsylvania.

Briles, W.E. 2001. Historical reivew of developments characterizing the B blood group system. In: K.A. Schat (ed.) Current Progress on Avian Immunology Research, pp. 155-161. American Association of Avian Pathologists, Kennett Square, Pennsylvania.

Medarova, A., W.E. Briles and R.L. Taylor, Jr. 2001. The effects of alloantigen system L on the fate of Rous sarcomas. In: K.A. Schat (ed.) Current Progress on Avian Immunology Research, pp. 215-219. American Association of Avian Pathologists, Kennett Square, Pennsylvania.

Senseney, H.L., H. Abplanalp, W.E. Briles and R.L. Taylor, Jr. 2001. Complementation between BQ and B17 MHC haplotypes increases Rous sarcoma regression. In: K.A. Schat (ed.) Current Progress on Avian Immunology Research, pp. 211-214. American Association of Avian Pathologists, Kennett Square, Pennsylvania.

LePage, K.T., W.E. Briles, F. Kopti and R.L. Taylor, Jr. 2000. Non-major histocompatibility complex effects on the fate of Rous sarcomas. Poultry Science 79:343-348. 

LePage, K.T., M.M. Miller, W.E. Briles and R.L. Taylor, Jr. 2000. Rfp-Y genotype affects the fate of Rous sarcomas in B2B5 chickens. Immunogenetics 51:751-754. 

Qureshi, M.A., R.A. Ali, L.N. Thomas, R.N. Baloch and W.E. Briles. 2000. Alloantigen systems L and P influence phagocytic function independent of the major histocompatibility complex (B) in chickens. Poultry Science 79:1271-1275. 

Kopti, F., S.L. Stevens, and W.E. Briles. 1999. Developmental expression of alloantigen systems in the chicken. Developmental & Comparative Immunology 23:617-627. 

Drake, B.M., R.M. Goto, M.M. Miller, G.F. Gee, and W.E. Briles. 1999. Molecular and immunogenetic analysis of major histocompatibility haplotypes in northern bobwhite enable direct identification of corresponding haplotypes in an endangered subspecies, the masked bobwhite. Zoo Biology 18:279-294. 

Maxey, G.D., E.M. Hollerman and W.E. Briles. 1997. Phenotypic variability in pedigreed families of goldfish revealed by alloantisera and agglutination assays. Journal of Aquatic Animal Health 9:49-57.

Kopti, F., R.W. Briles and W.E. Briles. 1997. Immunogenetics of the A-E alloantigen complex. Poultry Science 76:1688-1697.Jarvi, S.J., R.M. Goto, G.F. Gee, W.E. Briles, and M.M. Miller. 1999. Identification, inheritance, and linkage of B-G-like and MHC class genes in cranes. Journal of Heredity 90:152-159. 

Jarvi, S.I., R.M. Goto, W.E. Briles, and M.M. Miller. 1996. Characterization of Mhc genes in a multigenerational family of ring-necked pheasants. Immunogenetics 43:125-135.

Miller, M.M., R. Goto, R.L. Taylor, Jr., R. Zoorob, C. Auffray, R.W. Briles, W.E. Briles, and S.E. Bloom. 1996. Assignment of Rfp-Y to the chicken major histocompatibility complex/NOR microchromosome and evidence for high-frequency recombination associated with the nucleolar organizer region. Proc. Natl. Acad. Sci. USA 93:3958-3962.

Wakenell, P.S., M.M. Miller, R.M. Goto, W.J. Gauderman and W.E. Briles 1996. Association between the Rfp-Y haplotype and the incidence of Marek's disease in chickens. Immunogenetics 44:242-245.   

Research Interests

Photo of Chickens in cage
Current research deals with the expression of genes through cell-surface antigens, cell surface control of susceptibility and resistance to oncogenic viruses, immune response to neoplastic tissue, and genetic fine structure of the major histocompatibility complex (MHC) in the chicken.